منابع مشابه
Enzymic Catalysis
The time of greatest sensitivity to radiation is during the period of organogenesis in the first twelve weeks of human foetal development. Irradiation of the adult can cause life shortening or increased incidence of leukemia. The last chapter is concerned with the basis and origin of radiation protection standards, the hazards of nuclear power plants, high altitude supersonic aerospace travel, ...
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Recombinant unmethylated heterogeneous nuclear ribonucleoprotein particle (hnRNP) protein A1 was enzymatically methylated by nuclear protein/histone protein methylase I [Rajpurohit, Lee, Park, Paik and Kim (1994) J. Biol. Chem. 269, 1057-1082] and the effect of methylation on several physiocochemical properties was studied. The relative binding-affinity of methylated and unmethylated protein A1...
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Incubation of 6-phosphogluconate dehydrogenase from Candida utilis with either acetyl phosphate, 1,3-diphosphoglycerate or carbamoyl phosphate results in the phosphorylation of the protein. The binding of one phosphate residue per enzyme subunit does not affect significantly the kinetic properties, but makes the enzyme less reactive toward thiol reagents, trypsin and pyridoxal 5'-phosphate. We ...
متن کاملEnzymic degradation of heparin.
A sulphamidase and a sulphoesterase were isolated from adapted cells of Flavobacterium heparinum. These enzymes were partially purified from the 'heparinases' present in the bacterial extracts and characterized. The sulphamidase has a high specificity for glucosamine N-sulphate and glucosamine 2,6-disulphate. The activity decreases sharply with increasing molecular weight ofthe substrates teste...
متن کاملSimulations of enzymic reactions.
A fundamental problem in biology is the explanation of enzyme activity at the molecular level. The detailed origin of the rate acceleration of chemical reactions by enzymes is not fully understood, in spite of the immense amount of experimental work that has been done in this area [1,2]. T o describe an enzyme-catalysed reaction, its mechanism must be firmly established and intermediates must b...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1941
ISSN: 0306-3283
DOI: 10.1042/bj0350122